WebJun 26, 2002 · MAP kinases are part of a three-tiered cascade consisting of a MAP kinase, a MAP kinase kinase (MAPKK, MKK or MEK) and a MAP kinase kinase kinase (MAPKKK or MEKK). Phosphorylation of the threonine and tyrosine residues in the T-loop of the MAP kinase, by its upstream kinase, results in activation. WebHuang and Tan Cell & Bioscience 2012, 2:24 Cell & Bioscience REVIEW Open Access DUSPs, to MAP kinases and. ... 2:24 Cell & Bioscience REVIEW Open Access DUSPs, to MAP kinases and. sign in sign up. Dusps, to MAP Kinases and Beyond Ching-Yu Huang1* and Tse-Hua Tan1,2 [PDF] Related documentation. 9. Atypical Dusps: 19 Phosphatases in Search of a …
Dual-specificity MAP kinase phosphatases as targets of cancer
WebThis article is from Cell & Bioscience, volume 2.AbstractPhosphatases are important regulators of intracellular signaling events, and their functions have been... WebDual-specificity phosphatases (DUSPs), whose family currently contains 25 members, are phosphatases that can dephosphorylate both tyrosine and serine/threonine residues of … ordering pakistani clothes online
DUSPs, to MAP kinases and beyond. : Huang, Ching-Yu
WebJul 31, 2009 · to play a major role in development. Recent findings on the involvement of DUSPs in cancer progression and resistance will also be discussed. DUSP6; phosphorylation; phenotype THE MITOGEN-ACTIVATED PROTEIN KINASE (MAPK) family includes the extracellular-regulated kinases (ERKs) and the stress-acti-vated protein … WebJul 9, 2012 · It has been shown that DUSPs can modulate the function of MAP kinases by sequestering them in the cytoplasm or nucleus. These sequestrations may serve to retain … WebJul 12, 2024 · Dual-specificity phosphatases (DUSPs) are particularly interesting among all protein phosphatases 5, 6, 7. DUSPs, defined by sequence homology to MAP kinase phosphatases (MKPs), are named for... ordering pamphlets from cdc