Soft text trials

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August undefined, 2024

WebDec 9, 2024 · In the three-arm SOFT trial, the 12-year DMFS rates were 87.8% with AI-OFS, 86.2% with tamoxifen-OFS, and 84.8% with tamoxifen alone. In a combined analysis of … WebDec 23, 2024 · Updated analysis of the combined SOFT plus TEXT trials After a median follow-up of 12 – 13 years, the reduction in the risk of recurrence with 5-year of adjuvant …

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WebJul 8, 2024 · 5. 2024 Update of SOFT & TEXT trial • adding ovarian function suppression to tamoxifen significantly decreased the relative risk of disease-free survival events by 24% … WebDec 28, 2016 · SOFT & TEXT Trials 1. Presented by: Dr. Satyajeet Rath Guided by: Dr. Shantanu Sapru Date: 28-10-16 Prudence A. Francis et al., N Engl J Med 2015;372:436-46 … chingford optician

SABC San Antonio Breast Cancer Symposium 2024 SOFT/TEXT …

WebFeb 16, 2024 · In 2013, two randomized trials were initiated by the International Breast Cancer Study Group: The Suppression of Ovarian Function Trial (SOFT) and the … WebAug 20, 2024 · The SOFT-TEXT trial found that OFS+steroidal AI (EXM) had a better 5-year DFS than OFS+TAM. However, there was no statistic difference between the 2 groups in … WebThe SOFT and TEXT clinical trials produced practice changing results in the treatment of breast cancer in young women, who may have a poorer long-term prognosis. The research … grangetown nursery cardiff

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WebSOFT and TEXT are complementary trials, conducted over the same period of time and on the same patient population. Patients were randomly assigned in the following treatment … grangetown pavilion projectWebJan 3, 2024 · According to the investigators, the 3-year rate of breast cancer–free interval failure was similar to that of a comparative external control cohort from the SOFT/TEXT … grangetown police station cardiff

"WebJan 3, 2024 · According to the investigators, the 3-year rate of breast cancer–free interval failure was similar to that of a comparative external control cohort from the SOFT/TEXT trials (8.9% vs. 9.2%). Of the 497 patients who were followed for pregnancy status, 74.0% had at least one pregnancy, and 63.8% had at least one live birth; a total of 365 babies … " - Soft text trials

Soft text trials

Suppression of Ovarian Function With Either Tamoxifen or …

WebAug 7, 2003 · Patient-reported outcomes with adjuvant exemestane versus tamoxifen in premenopausal women with early breast cancer undergoing ovarian suppression (TEXT … WebMar 30, 2024 · Enrollment in the TEXT and SOFT trials. (A) TEXT: Between November 2003 and April 2011, TEXT enrolled 2672 patients; enrollment was suspended 1 December …

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WebFeb 3, 2024 · We obtained data from all four identified trials (ABCSG XII, SOFT, TEXT, and HOBOE trials), which included 7030 women with ER-positive tumours enrolled between … WebDec 17, 2024 · Over all four trials, median follow-up was 8.0 years. In the ABCSG-12 trial 5% of patients received neoadjuvant chemotherapy. In TEXT, 60% of patients received …

WebDec 8, 2024 · All women had undergone ovarian suppression or ablation and were randomly assigned to either an AI or tamoxifen for 3 years (ABCSG XII trial) or 5 years (SOFT, TEXT, and HOBOE trials). WebDec 16, 2024 · Secondary analysis of SOFT and TEXT trials results in development of a risk score to guide decision making in adjuvant endocrine therapy for premenopausal women …

WebDec 9, 2024 · Trial participants were strongly recommended to resume endocrine therapy after a pregnancy attempt or success. To date, 76.3 percent have resumed their therapy, the authors said. Partridge and Pagani said the study provides encouraging guidance to younger women diagnosed with breast cancer who may be hoping to have children. WebMeredith M. Regan, ScD, Harvard Medical School, Boston, MA, gives an update on the 12-year follow-up results of the SOFT (NCT00066690) and TEXT (NCT00066703)...

Web2 days ago · Aim: This randomized controlled trial aimed to investigate the efficacy of soft-tissue augmentation (STA) with a subepithelial connective tissue graft (SCTG) or an acellular dermal matrix (ADM) on ...

WebApr 7, 2024 · Malakoplakia is a rare condition characterized by inflammatory masses with specific histological characteristics. These soft tissue masses can mimic tumors and tend to develop in association with chronic or recurrent infections, typically of the urinary tract. A specific defect in innate immunity has been described. In the absence of randomized … chingford overgroundWebDec 15, 2012 · Background: The SOFT and TEXT randomized phase 3 trials address two primary questions for endocrine treatment of premenopausal women with hormone … chingford overground lineWebApr 7, 2024 · Peri-Implant Soft Tissue Integration in Humans: Influence of Material The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by … grangetown postcodeWebThe landscape of adjuvant endocrine therapy in premenopausal women has changed significantly since the joint analysis of the SOFT and TEXT trials.7 These data had a … grangetown pharmacy middlesbroughWebJun 16, 2015 · In this regard, in the SOFT and TEXT trials, endocrine side-effects were quite similar in women with or without previous or concurrent chemotherapy administration. … chingford parish church choirWebJun 1, 2014 · The TEXT and SOFT trials were phase III, randomized clinical trials that enrolled 2,672 and 3,066 premenopausal women with hormone receptor-positive early … grangetown nursery school cardiffWebMar 10, 2024 · The benefits of ovarian function suppression were sustained long term for premenopausal women with hormone receptor–positive breast cancer, according to … grangetown primary middlesbrough